You Searched For: SOUTHERN BIOTECHNOLOGY MS

Catalog Number: (100242-972)

Supplier: Southern Biotechnology

Description: Biotin Anti-Type III Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, and western blotting assays.

Catalog Number: (100245-142)

Supplier: Southern Biotechnology

Description: Rabbit Anti-Goat IgG(H+L)-FITC antibody for use in immunohistochemistry / immunocytochemistry and western blotting assays.

Catalog Number: (100242-480)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG-TRITC antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.

Supplier: Southern Biotechnology

Description: PE Anti-Mouse IgE antibody for use in flow cytometry assays.

Supplier: Southern Biotechnology

Description: ZAP-70 is a protein tyrosine kinase (PTK) with the primary role of catalyzing the phosphorylation of tyrosine residues in cellular proteins, and thus, contributes significantly to the initiation of cell signaling. ZAP-70 is normally expressed on T cell and NK cells.

Catalog Number: (100243-222)

Supplier: Southern Biotechnology

Description: CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.

Catalog Number: (100243-326)

Supplier: Southern Biotechnology

Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.

Catalog Number: (100242-526)

Supplier: Southern Biotechnology

Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-HRP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

Catalog Number: (100243-088)

Supplier: Southern Biotechnology

Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.

Catalog Number: (100243-174)

Supplier: Southern Biotechnology

Description: In the mouse, CD8 exists in two forms – (i) a CD8 heterodimer composed of an α chain (CD8α) and a β chain (CD8β); and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the “suppressor/cytotoxic” subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8α without CD8β. It has been suggested that CD8+β- T cells mature extrathymically, while development of the CD8α+β+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8α+ cells. The 53-6.7 monoclonal antibody also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.

Catalog Number: (100242-230)

Supplier: Southern Biotechnology

Description: Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.

Catalog Number: (100242-396)

Supplier: Southern Biotechnology

Description: Purified Anti-Mouse IL-4 antibody for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, ELISA, and ELISpot assays.

Catalog Number: (100241-954)

Supplier: Southern Biotechnology

Description: Mouse IgG3-FITC for use as a control in flow cytometry and immunocytochemistry assays.

Catalog Number: (100241-996)

Supplier: Southern Biotechnology

Description: Mouse IgG-PE/CY5 (SPRD) for use as a control in flow cytometry assays.

Catalog Number: (100244-640)

Supplier: Southern Biotechnology

Description: FITC Anti-Rat Kappa antibody for use in flow cytometry, ELISA, immunohistochemistry, and western blotting assays.

Catalog Number: (100245-118)

Supplier: Southern Biotechnology

Description: Purified Rabbit Anti-Sheep IgG(H+L) antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.