Anti-Bcl-xL Mouse Monoclonal Antibody (Biotin) [clone: 7B2.5]

Supplier: Southern Biotechnology
10030-08
100242-230EA 461.62 USD
100242-230
Anti-Bcl-xL Mouse Monoclonal Antibody (Biotin) [clone: 7B2.5]
Antibodies
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.

Type: Primary
Antigen: Bcl-xL
Clonality: Monoclonal
Clone: 7B2.5
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human, Mouse, Rat, Rhesus
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