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Catalog Number: (102512-148)
Supplier: Adipogen
Description: Human CD24 is a glycosyl phosphatidyl inositol (GPI) anchored surface protein found on B cells during multiple stages of development from precursor to the onset of plasma cell differentiation. Expression of CD24 has been observed to be a lineage predictor in AML.

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Catalog Number: (102512-128)
Supplier: Adipogen
Description: Human CD22 expression is restricted to normal Ig+ mature B cells and neoplastic B cells. CD22 is a transmembrane glycoprotein of 140kDa with a predicted adhesion molecule function.

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Catalog Number: (102512-518)
Supplier: Adipogen
Description: Human CD63 is expressed on activated platelets and also on monocytes and macrophages. CD63 contains four hydrophobic transmembrane regions and is a member of the tetraspan family. CD63 appears to be involved with cell adhesion and associates with VLA-3 and VLA-6 integrins. In a colon cancer model, it has been correlated to metastatic potential.

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Catalog Number: (102512-552)
Supplier: Adipogen
Description: Human CD69 is expressed by platelets and mature thymocytes and appears rapidly after activation on T cells, B cells and NK cells. This pattern of cellular CD69 expression has suggested a lymphocyte activation role. Functional studies with antibodies to CD69 also support an activation role for CD69.

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Catalog Number: (102512-512)
Supplier: Adipogen
Description: Human CD63 is expressed on activated platelets and also on monocytes and macrophages. CD63 contains four hydrophobic transmembrane regions and is a member of the tetraspan family. CD63 appears to be involved with cell adhesion and associates with VLA-3 and VLA-6 integrins. In a colon cancer model, it has been correlated to metastatic potential.

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Catalog Number: (102512-464)
Supplier: Adipogen
Description: Human CD55 is a GPI anchored protein that can protect cells from complement mediated lysis.

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Catalog Number: (102512-488)
Supplier: Adipogen
Description: Human CD58 is a cell surface glycoprotein with wide distribution on hemopoietic cells and functions as an adhesion molecule mediating a costimulatory signal through CD2. CD58 is attached to the cell surface by either of two forms - transmembrane or GPI.

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Catalog Number: (102512-494)
Supplier: Adipogen
Description: Human CD59 is a GPI anchored molecule that protects cells from complement-mediated lysis. Studies are progressing to determine the regulatory mechanism for CD59 expression. A CD59-like protein has been discovered on the causative agent of Amebic encephalitis.

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Supplier: Adipogen
Description: NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

Catalog Number: (102513-402)
Supplier: Adipogen
Description: CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.

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Catalog Number: (102514-336)
Supplier: Adipogen
Description: Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.


Catalog Number: (102514-362)
Supplier: Adipogen
Description: The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to caspase-1 activation. The NLR member IPAF/NLRC4 senses bacterial flagellin and a conserved type III secretion system (TTSS) rod component. A member of the NLR family, NAIP5 directly and specifically interacts with flagellin, triggers a physical NAIP5-NLRC4 association leading to NLRC4 activation. The related NAIP2 functions analogously to NAIP5, serving as a specific inflammasome receptor for TTSS rod proteins such as Salmonella PrgJ and Burkholderia BsaK.


Catalog Number: (102514-344)
Supplier: Adipogen
Description: PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.


Catalog Number: (102512-566)
Supplier: Adipogen
Description: Human CD71 is a type II transmembrane glycoprotein found on activated leukocytes. CD71 binds transferrin and mediates uptake of iron through endocytosis and recycling.

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Catalog Number: (102512-620)
Supplier: Adipogen
Description: Human CD62E (E-selectin) is an adhesion molecule expressed on activated endothelium and facilitates recruitment of leukocytes to sights of acute inflammation and immunological events. CD62E has affinity to Lewisx.

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Catalog Number: (102512-634)
Supplier: Adipogen
Description: The cytokine human interleukin-2 (IL-2) is a 15kDa protein expressed upon activation by peripheral TH1 cells, medullary thymocytes and a subset of large granular lymphocytes. Secreted IL-2 stimulates proliferation and lymphokine production by T cells, B cells and NK cells.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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