Anti-NQO1 Mouse Monoclonal Antibody [clone: Skiny-1]

Supplier: Adipogen

AG-20A-0086-C050 AG-20A-0086-C100

102514-226EA 138.46 USD

102514-226 102514-228

Anti-NQO1 Mouse Monoclonal Antibody [clone: Skiny-1]

Antibodies

NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

Type:
Antigen: NQO1
Clonality: Monoclonal
Clone: Skiny-1
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human

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