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Human CD137L (from CHO cells)

Catalog Number: (102513-228)
Supplier: Adipogen
Description: Human CD137L (4-1BB ligand) is a type II transmembrane protein constitutively expressed by monocytes, B cells and neuroblastoma cells. Binding of CD137 (4-1BB) to CD137L induces monocyte activation.

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Mouse Recombinant ANGPTL3 (from HEK293 cells)

Supplier: Adipogen
Description: ANGPTL3 (Angiopoietin-like protein 3) regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.

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Aspyrone ≥98% (by HPLC)

Supplier: Adipogen
Description: Aspyrone shows nematicidal, insecticidal, antibacterial and antifungal activity.

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Human CD273 (from CHO cells)

Catalog Number: (102979-342)
Supplier: Adipogen
Description: CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; programmed death molecule) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274.
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beta-Mannosylceramide ≥95% (by TLC, NMR)

Supplier: Adipogen
Description: Potent stimulator of invariant natural killer T (iNKT) cells. Induces strong antitumor immunity through a nitric oxide (NO) and TNF-alpha dependent mechansim, different compared to the IFN-gamma dependent mechanism of alpha-GalCer (AG-CN2-0014). Does not induce anergy of iNKT cells.

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Mouse Recombinant CD275 (from CHO cells)

Catalog Number: (102981-516)
Supplier: Adipogen
Description: Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
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Anthralin

Supplier: Adipogen
Description: Anthralin is a leukotriene biosynthesis inhibitor. It inhibits LTB4 omega-oxidation and disrupts mitochondria function. Anthralin is used in the treatment of psoriasis, as a fungicide, in the treatment of ringworm infections and in chronic dermatoses. It accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. Numerous studies have demonstrated anti-proliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. It is also used as matrix substance for MALDI-MS (matrix-assisted laser desorption ionization MS).

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Pyridoxal hydrochloride

Supplier: Adipogen
Description: For the labeling of amino acids and their detection in picomolar amounts.

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1-Chloro-1,2-benziodoxol-3-one ≥98% (by HPLC)

Supplier: Adipogen
Description: A Hypervalent iodine reagent for oxidation reactions.

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DPVP (Resveratrol Analog) (by NMR)

Catalog Number: (102988-738)
Supplier: Adipogen
Description: Anticancer compound. Shown to inhibit progression of prostate cancer cells. Anti-obesity agent. 3T3-L1 adipocyte differentiation and FAS expression inhibitor.
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Naphthomycin B (from Streptomyces sp. Gö 40/14) ≥98% (by HPLC)

Catalog Number: (102513-692)
Supplier: Adipogen
Description: Naphthomycin B is an ansamycin antibiotic.

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Human CD27 (from CHO cells)

Catalog Number: (102513-364)
Supplier: Adipogen
Description: Human CD27 is a lymphocyte specific member of the TNF receptor family and is found primarily on peripheral blood T cells and on a subpopulation of B cells and NK cells. The ligand for CD27 is CD70, which is a member of the TNF ligand superfamily.

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1-(3-Isothiocyanatobenzyl)-4-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)-5-oxazolyl] pyridinium bromide ≥90% (by HPCE)

Supplier: Adipogen
Description: Class of highly photostable, water soluble fluorescent labels with large Stoke′s shift, high QY in aqueous media and pH tolerance. Relatively low extinction coefficient (Epsilon∼ <gt/>20,000 in EtOH).

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Human CD95 (from CHO cells)

Catalog Number: (102513-246)
Supplier: Adipogen
Description: Human CD95 (APO-1; Fas) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for regulating the immune response.

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Enalaprilat ≥99% (by HPLC)

Supplier: Adipogen
Description: Active metabolite enalapril. Nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor. Shown to improve cardiac preservation via bradykinin receptor and PKC without affecting ATP metabolism. Has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway. Increases PPARbeta/delta expression, without influence on PPARalpha and PPARgamma.

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Dihydromanumycin A ≥95% (by TLC, NMR)

Catalog Number: (102981-214)
Supplier: Adipogen
Description: Dihydromanumycin A is a derivative of Manumycin A.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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