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Catalog Number: (102515-714)
Supplier: Adipogen
Description: Ligand of DAF-12, an orphan nuclear receptor, that regulates dauer diapause, reproductive development, fat metabolism, and life span (life cycle) in parasitic nematodes. Sterol-derived hormone. Blocks formation of infective larvae in several parasitic nematodes. Inhibits the dauer-promoting activity of DAF-12. Supports the reproductive development.

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Catalog Number: (102513-536)
Supplier: Adipogen
Description: Pyrrolcarbonyltaloside is an antibiotic.

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Catalog Number: (102989-084)
Supplier: Adipogen
Description: Dimeric spiro-azaphilone. Mycotoxin.


Catalog Number: (102981-522)
Supplier: Adipogen
Description: CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting cells and display extracellular regions containing immunoglobulin (Ig) variable (V)- and constant (C)-like domains, are known to modulate T cell receptor (TCR)-mediated T cell activation by providing co-signals that are either stimulatory or inhibitory. B7-H3 provides a stimulatory signal to T cells. However, recent studies suggest a negative regulatory role for B7-H3 in T cell responses. B7-H3 inhibited T cell proliferation mediated by antibody to T cell receptor or allogeneic antigen-presenting cells. B7-H3 is a negative regulator that preferentially affects T(H)1 responses. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. Recently, B7-H3 expression has also been found in a variety of different human cancers, including prostate cancer, clear cell renal cell carcinoma (ccRCC), non-small-cell lung cancer (NSCLC), pancreatic cancer, gastric cancer, ovarian cancer, colorectal cancer (CRC) and urothelial cell carcinoma. B7-H3 was expressed in some human cancers and correlated with poor outcome of cancer patients.


Catalog Number: (102515-676)
Supplier: Adipogen
Description: Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.

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Catalog Number: (102513-212)
Supplier: Adipogen
Description: Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. This product is a soluble fusion protein combining the extracellular (125aa) domain of human CD152 and murine IgG2a Fc (CTLA-4 Ig).

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Catalog Number: (102988-048)
Supplier: Adipogen
Description: Antiprotozoal (Leishmania). Antifungal.


Catalog Number: (102511-350)
Supplier: Adipogen
Description: Human CD83 is a 40-50 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.

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Catalog Number: (102512-542)
Supplier: Adipogen
Description: Human CD66e is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. Soluble CD66e is also known as carcinoembryonic antigen (CEA).

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Catalog Number: (102512-536)
Supplier: Adipogen
Description: Human CD66e is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. Soluble CD66e is also known as carcinoembryonic antigen (CEA).

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Supplier: Adipogen
Description: Albocycline is a 14-membered macrolide antibiotic without sugar moieties.

Supplier: Adipogen
Description: Building block for synthesis. Frequently used as precursors to di-tert-butylcyclopentadienyl (Cpt) ligand in many sandwich and half sandwich complexes. Di-tert-butylcyclopentadiene reacts with excess potassium tert-butoxide in the presence of elemental selenium to yield cyclopentadienes bridged by two or three selenium atoms through one or two diselenoketal functionalities. It reacts with excess potassium tert-butoxide in the presence of elemental sulfur to yield cyclopentadienes bridged by sulfur atoms via one or two dithioketal functionalities.

Catalog Number: (102981-224)
Supplier: Adipogen
Description: The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.


Supplier: Adipogen
Description: Reactant for: (1) preparation of unsaturated hydroxymethylene diphosphonic acid derivatives by reaction of trimethylsilyl phosphites, (2) asymmetrical synthesis of the isoindolinone subunit of the macrocyclic poylketide natural product muironolide via stereoselective intramolecular Diels-Alder cycloaddition, (3) preparation of emollient, humectant, and fluorescent alpha,beta-unsaturated thiol esters for long-acting skin applications, (4) stereoselective synthesis of enediol carbonates for use in the asymmetrical synthesis of alpha-acyloxyketones, (5) acylation of pyrazoles.

Catalog Number: (102988-906)
Supplier: Adipogen
Description: Modified base of mammalian DNA. Involved in regulation of stem cell processes, cellular development, neurodegeneration and carcinogenesis. Important epigenetic marker. Related to bacimethrin .


Supplier: Adipogen
Description: IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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