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You Searched For: Proteins and Peptides

Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.

Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.


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Product Image-77751-018

Human Recombinant FGF-6 (from E. coli)

Supplier: VWR International
Description: Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.

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Product Image-77750-824

Human Recombinant FGF-10 (from E. coli)

Supplier: VWR International
Description: <p>Fibroblast growth factor 10 (FGF-10) is a growth factor that is important during embryonic development, especially during lung, limb, brain, heart, and kidney morphogenesis. FGF-10 is expressed in mesenchymal cells and facilitates epithelial-mesenchymal signaling through binding the epithelially expressed FGF receptor 2b (FGFR2b). FGF-10 also functions as a mitogen for keratinizing epidermal cells, and induces the migration and invasion of cancer cells.</p>

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Product Image-77750-196

Human Recombinant TNF-A (from E. coli)

Supplier: VWR International
Description: Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

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Product Image-77750-764

Human Recombinant EOTAXIN (from E. coli)

Supplier: VWR International
Description: Eotaxin, also known as eotaxin-1 and CCL11, is a chemokine that recruits eosinophils to sites of allergic inflammation. Eotaxin signals through the G protein-coupled chemokine receptors CCR2, CCR3, and CCR5. Eotaxin also negatively regulates adult neurogenesis, and high eotaxin levels are associated with impaired learning and memory.

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Product Image-77750-274

Human Recombinant I-TAC (from E. coli)

Supplier: VWR International
Description: Interferon-inducible T cell alpha chemoattractant (I-TAC), or CXCL11, is expressed at high levels in leukocytes, pancreas, and liver cells. I-TAC gene expression is induced by interferons alpha (IFN-α), beta (IFN-β), and gamma (IFN-ɣ). I-TAC is the dominant ligand known to bind the chemokine receptor CXCR3, thus acting as a stronge agonist. I-TAC functions as a chemoattractant for interleukin 2 (IL-2)-activated T cells.

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Product Image-77750-458

Human Recombinant FGF-21 (from E. coli)

Supplier: VWR International
Description: Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.

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Product Image-77750-718

Human Recombinant GDF-15-D Mutant (from E. coli)

Supplier: VWR International
Description: <p>Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure. The GDF-15 D variant has a Histidine to an Aspartate substitution at amino acid position 7.</p>

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Product Image-77750-524

Human Recombinant MIF (from E. coli)

Supplier: VWR International
Description: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin 1 (IL-1), interleukin 8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-gamma-activated macrophages, MIF stimulates nitric oxide (NO) production and tumor necrosis factor-alpha (TNF-α) secretion. 

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Product Image-77750-262

Human Recombinant IP-10 (from E. coli)

Supplier: VWR International
Description: Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells and fibroblasts in response to interferon gamma (IFN-ɣ). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3.

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Product Image-77750-510

Human Recombinant IL-17F (from E. coli)

Supplier: VWR International
Description: Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes.  IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines.  IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-b1).  

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Product Image-77750-038

Human Recombinant GDNF (from E. coli cells)

Supplier: VWR International
Description: Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

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Product Image-77750-396

Human Recombinant IL-16 (from E. coli)

Supplier: VWR International
Description: Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin 2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).

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Product Image-77750-410

Human Recombinant IL-33 (from E. coli)

Supplier: VWR International
Description: Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.

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Product Image-77752-944

Rat Recombinant MCP-1 (from E. coli)

Supplier: VWR International
Description: Monocyte chemotactic protein 1 (MCP-1), also known as CCL2, is produced by injured or infected tissues. MCP-1 signals through the CCR2 and CCR4 G protein-coupled receptors to recruit memory T cells, monocytes, and dendritic cells to sites of inflammation.

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Product Image-77753-068

Rat Recombinant IL-2 (from E. coli)

Supplier: VWR International
Description: Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

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Product Image-77753-072

Rat Recombinant IL-2 (from E. coli)

Supplier: VWR International
Description: Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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