You Searched For: Antibodies

Catalog Number: (RL600401J02)

Supplier: Rockland Immunochemical

Description: Anti-Histone H4 [Dimethyl Lys20] antibody is useful for Western Blot, Dot Blot, Chromatin Immunoprecipitation, Immunofluorescence, and Immunocytochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately

Catalog Number: (RL610406C46)

Supplier: Rockland Immunochemical

Description: Anti-Mouse IgG subclass pan reactive Secondary Antibody is suitable for highly specific immunological methods requiring extremely low background levels, lot-to-lot consistency, high titer and specificity.

Catalog Number: (RL6031440020.5)

Supplier: Rockland Immunochemical

Description: Anti-IgG Goat Polyclonal Antibody (DyLight® 680)

Catalog Number: (RL6054420020.5)

Supplier: Rockland Immunochemical

Description: Anti-IgG Rabbit Polyclonal Antibody (DyLight® 549)

Catalog Number: (RL605-306-002)

Supplier: Rockland Immunochemical

Description: Anti-IgG Mouse Polyclonal Antibody (Biotin)

Catalog Number: (RL605-301-002)

Supplier: Rockland Immunochemical

Description: Anti-IgG Mouse Polyclonal Antibody

Catalog Number: (RL605-9902)

Supplier: Rockland Immunochemical

Description: Anti-IgG Chicken Polyclonal Antibody (Texas Red®)

Supplier: Enzo Life Sciences

Description: Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.

SDS

Catalog Number: (95042-156)

Supplier: Enzo Life Sciences

Description: The diffusible free radical gas nitric oxide (NO) affects a variety of physiological functions, and is a key regulator of the cardiovascular, nervous, and immune systems. NO is synthesized in many tissues from L-arginine, oxygen, and NADPH by three known isoforms of a heme-containing flavoprotein termed NO synthase (nNOS/NOS-I, iNOS/NOS-II, and eNOS/NOS-III). nNOS is a constitutively expressed neuronal NOS isoform that exits in its latent form until it is activated by the binding of calmodulin follo wing elevation of intracellular calcium levels. The C-terminus of nNOS contains a conserved serine residue, Ser1417, analogous to Ser1177 of the constitutively expressed endothelial NOS isoform (eNOS). Phosphorylation of Ser1417 is believed to regulate nNOS activation, particularly in glucose-sensing neurons, where inhibition of AMPK pathways by glucose and leptin serve to suppress nNOS activity, whereas activation of AMPK by insulin leads to nNOS activation.

SDS

Catalog Number: (95040-502)

Supplier: Enzo Life Sciences

Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Catalog Number: (95038-602)

Supplier: Enzo Life Sciences

Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Catalog Number: (RL604-4903)

Supplier: Rockland Immunochemical

Description: Secondary Rabbit Anti-IgG F(c) Reacts with Dog (Canine)

Catalog Number: (RL604-4304)

Supplier: Rockland Immunochemical

Description: Secondary Rabbit Anti-IgG F(ab')2 Reacts with Dog (Canine)

Catalog Number: (RL609-103-123)

Supplier: Rockland Immunochemical

Description: Peroxidase Secondary antibody reagents are ideal for western blotting, immunochemistry and ELISA as well as other antibody detection methods.

Catalog Number: (RL606-1202)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Guinea Pig

Catalog Number: (RL603-4902)

Supplier: Rockland Immunochemical

Description: Secondary Rabbit Anti-IgY Reacts with Chicken