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Image Unavailable-75842-370

Anti-TLR4 Mouse Monoclonal Antibody [clone: HTA125]

Catalog Number: (75842-370)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
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Anti-TLR3 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: TLR3.7]

Catalog Number: (75842-356)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3), a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. It is expressed by dendritic cells and recognize double-stranded RNA and polyinosine-polycytidylic acid. Upon ligand binding, CD283 induces type I interferon production and activation of the nuclear factor kappa-light-chain-enhancer of activated B cells complex (NF-κB).
Image Unavailable-75842-428

Rat IgG2a, kappa Isotype Control (BG Violet 450) [clone: 2A3]

Catalog Number: (75842-428)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 2A3 antibody was obtained by hybridization of MouseNS-1 myeloma cells with spleen cells harvested from BALB/c mice immunized with phytohemagglutinin-activated human T cells. The 2A3 antibody is a CD25 clone and used as an Isotype Control for rat IgG2a antibodies. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Image Unavailable-75842-324

Anti-ENG Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: SN6]

Catalog Number: (75842-324)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The SN6 monoclonal antibody specifically reacts with human CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells, activated macrophages, and a subset of bone marrow cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
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Anti-CD278 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: ISA-3]

Catalog Number: (75842-396)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS), a 47-60 kDA homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4,5,10 in T cells.
Image Unavailable-75842-492

Mouse IgG2a Isotype Control (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: C1.18.4]

Catalog Number: (75842-492)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The C1.18.4 monoclonal antibody is used as an Isotype Control for MouseIgG2a antibodies. It has unknown specificity and occurred spontaneously in a C3H mouse.
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Anti-HLA-DR Mouse Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: LN3]

Catalog Number: (75842-512)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The LN3 monoclonal antibody specifically reacts with the human leukocyte antigen-DR (HLA-DR), a MHC class II heterodimeric surface glycoprotein. HLA-DR is expressed on the antigen presenting surfaces of monocytes, macrophages, dendritic cells, activated T cells, and B cells. It is integral to peptide presentation to CD4+ T cells.
Image Unavailable-75842-462

Rat IgG2b Isotype Control (APC (Allophycocyanin)) [clone: LTF-2]

Catalog Number: (75842-462)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The LTF-2 monoclonal antibody is used as an Isotype Control immunoglobulin for rat IgG2b antibodies.
Image Unavailable-75842-460

Rat IgG2b Isotype Control (PE (Phycoerythrin)-Cy7®) [clone: LTF-2]

Catalog Number: (75842-460)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The LTF-2 monoclonal antibody is used as an Isotype Control immunoglobulin for rat IgG2b antibodies.
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Rat IgG2b, kappa Isotype Control (PE (Phycoerythrin)) [clone: LTF-2]

Catalog Number: (75842-454)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The LTF-2 monoclonal antibody is used as an Isotype Control immunoglobulin for rat IgG2b antibodies.
Image Unavailable-75842-552

Anti-Ly-6G Rat Monoclonal Antibody (BG Violet 450) [clone: RB6-8C5]

Catalog Number: (75842-552)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1). The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.
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Anti-Ly-6G Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: RB6-8C5]

Catalog Number: (75842-560)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1). The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.
Image Unavailable-75842-662

Anti-Fc epsilon Receptor I alpha (FceR1) (MAR-1) Armenian Hamster Monoclonal Antibody [clone: 42795]

Catalog Number: (75842-662)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc ε Receptor I α subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
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Anti-Foxp3 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: 3G3]

Catalog Number: (75842-606)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy” mice phenotype.
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Anti-CD20 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 2H7]

Catalog Number: (75842-740)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
Image Unavailable-75842-806

Anti-CD11a Rat Monoclonal Antibody [clone: M17/4]

Catalog Number: (75842-806)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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