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Collagenase Chromophore Substrate Test Substance

Supplier: Adipogen
Description: Enzyme substrate.

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Viomellein ≥96% (by HPLC)

Supplier: Adipogen
Description: Genotoxic mycotoxin. Antibacterial (Gram-positive) and insecticidal. Aromatase inhibitor.

Small Business Enterprise

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Ferimzone ≥98% (by HPLC)

Supplier: Adipogen
Description: Systemic fungicide developed for the control of rice diseases that exhibits strong antifungal activity against many plant-pathogenic fungi. Antifungal activity does not affect the synthesis of RNA, DNA, protein, cell walls, or lipid components. Inhibits mycelial growth, but does not inhibit spore germination until a germ tube had formed. No effect of ferimzone was observed on the cell wall architecture of mycelia. Ferimzone causes leakage of some electrolytes from mycelia, which suggests that it affects or disrupts membrane function. Compound can be used as analytical reference material.

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N-Octadecanoyl-Nile Blue ≥98% (by TLC)

Supplier: Adipogen
Description: This membrane probe has been used as an optode sensor for sodium and other ions. It was used to set up optical dihydrogen phosphate-selective sensors better suited for operation at physiological pH than their ion selective electrode counterparts.

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N-(4-Methylumbelliferyl)-maleinimide ≥95% (by HPLC)

Supplier: Adipogen
Description: Fluorescent reagent with high selectivity.

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Ac-Arg-Leu-Arg-AMC

Supplier: Adipogen
Description: Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

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Kaempferitrin ≥98% (by NMR)

Supplier: Adipogen
Description: Cytotoxic and anti-inflammatory compound (weak). Antioxidant. Lipid peroxidation inhibitor. Free radical scavenger. Inhibitor of myeloperoxidase activity. Hypoglycemic. Decreases blood glucose levels in diabetic and normal rats. Insulinomimetic. Modulates glucose homeostasis. Decreases blood glucose levels and stimulates glucose uptake in muscle. Inhibits GLUT4 mediated glucose uptake in differentiated 3T3-L1 cells. Improves insulin resistance by the activation of the classical insulin transduction pathway. Increases adiponectin secretion in 3T3-L1 adipocytes. Antinoniceptive. May have antidyslipidemic activity.

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Chaetoglobosin A (from Chaetomium sp.) ≥98% (by HPLC)

Supplier: Adipogen
Description: Chaetoglobosin A is a cytochalasan analog with anti-fungal activity.

Small Business Enterprise

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TAK-285 ≥95%

Supplier: Adipogen
Description: TAK-285 is a novel investigational dual HER2/EGFR inhibitor with IC(50) values of 17 and 23nM, respectively.

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FOAA ≥90% (by HPCE)

Supplier: Adipogen
Description: Fluorescent label which reacts with amines after activation to give isomerically homogeneous derivatives.

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Human CD127 (from CHO cells)

Catalog Number: (102513-348)
Supplier: Adipogen
Description: CD127 (IL-7Ra) is the specific receptor component for the cytokine interleukin -7 (IL-7). It is found on a wide variety of hematopoietic cell types including B cell precursors and the majority of T cells. Its expression levels are decreased on T cells following activation. CD127 can dimerize with CD132 (IL-2Rgamma) to form a high affinity IL-7 receptor. CD127 engagement is necessary for T cell development in humans.

Small Business Enterprise


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Human Recombinant Annexin (from E. coli), ATTO 488

Catalog Number: (102511-442)
Supplier: Adipogen
Description: Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

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Cyclopenol ≥95% (by HPLC)

Catalog Number: (102988-036)
Supplier: Adipogen
Description: Antimicrobial. Phytotoxic.
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NAD Kinase (from E. coli)

Catalog Number: (102980-448)
Supplier: Adipogen
Description: NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions
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Human CD275 (from CHO cells)

Catalog Number: (102513-370)
Supplier: Adipogen
Description: The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.

Small Business Enterprise


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Vincristine sulfate

Supplier: Adipogen
Description: Immunosuppressant. Anticancer compound. Chemotherapeutic agent. Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins. Apoptosis inducer and cell cycle inhibitor in G2/M phase. Autophagy inhibitor. Inhibits microtubule-mediated fusion of autophagosome with lysosme. Inducer of IL-1beta production. Activates alone and synergistically together with doxorubicin the NLRP3-inflammasome mediated processing of IL-1beta. Monoamine oxidase (MAO) inhibitor.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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