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Catalog Number: (103002-744)

Supplier: Anaspec Inc

Description: This is a fluorescent (FITC)-labeled Erythropoietin (EPO)-mimetic peptide (EMP17), Abs/Em=494/520 nm. Erythropoietin (EPO) is the hormone involved in red blood cell production, which activates its receptor by binding to the receptor's extracellular domain and presumably dimerizing two receptor monomers to initiate signal transduction. EMP contains two potentially reactive amines, one at the amino terminus of the peptide and one in the side chain of the single lysine within the peptide sequence.
Sequence: FITC-LC-TYSCHFGPLTWVCKPQGG
MW: 2483.9 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (103008-718)

Supplier: Anaspec Inc

Description: Gliadin is a gluten component. This peptide is derived from amino acid residues 57-68 of a9-gliadin and represents an immunodominant epitope that has been shown to elicit HLA-DQ2-restricted T-cell responses in celiac patients. This epitope is resistant to pancreatic proteolysis.
Sequence: QLQPFPQPQLPY
MW: 1455.7 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (102996-530)

Supplier: Anaspec Inc

Description: Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin. Upon cleavage by proprotein convertase 2 (PC2), multiple active peptides are released: dynorphin A, dynorphin B, and α/β-neo-endorphin. Dynorphins exert their effects primarily through the κ-opioid receptor (KOR), a G-protein-coupled receptor. Dynorphin has been shown to be a modulator of pain response, involved in drug addiction and appetite control.
Sequence:YGGFLRRI
MW:981.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (102996-570)

Supplier: Anaspec Inc

Description: The native peptide,RRLIEDAEYAARG (cat# 22581), is derived from pp60src, and considered to be a generic substrate for various protein tyrosine kinases. The fluorescent and biotinylated peptides are used to design a variety of assays for PTKs.
Sequence:RRLIEDAE-pY-AARG
MW:1599.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103011-396)

Supplier: Anaspec Inc

Description: Calcein, AM is a cell-permeant and non-fluorescent compound that is widely used for determining cell viability

Catalog Number: (103011-388)

Supplier: Anaspec Inc

Description: Reactive pH indicator for slightly acidic pH range

Catalog Number: (103011-378)

Supplier: Anaspec Inc

Description: BSB, derived from the structure of Congo Red, is shown to bind to a wide range of amyloid inclusions in situ.

Catalog Number: (103011-326)

Supplier: Anaspec Inc

Description: Bind to DNA/RNA (red fluorescence) upon oxidation. Store at -20C desiccated and protected from light

Catalog Number: (103011-314)

Supplier: Anaspec Inc

Description: Unlike FDG that requires a two-step hydrolysis to generate maximum fluorescence, resorufin β-D-galactopyranoside requires only a single-step hydrolysis reaction to attain full fluorescence. This substrate is especially useful for sensitive enzyme measurements in ELISAs. The relatively low pKa (~6.0) of resorufin (the enzymatic hydrolysis product of resorufin galactoside) with Ex/Em=573/585 nm permits continuous measurement of enzymatic activity. Resorufin galactoside has also been used to quantitate β-galactosidase activity in single yeast cells by flow cytometry and to detect immobilized β-galactosidase activity.

Catalog Number: (103010-534)

Supplier: Anaspec Inc

Description: Cathepsin B is a member

Catalog Number: (103010-520)

Supplier: Anaspec Inc

Description: Glutathione (GSH) is an important antioxidant molecule that functions as a cofactor for a variety of enzymes and is involved in various biological processes

Catalog Number: (103010-514)

Supplier: Anaspec Inc

Description: Histone deacetylase (HDAC) enzymes act as transcriptional repressors of genes through the deacetylation of lysine residues on histone proteins

Catalog Number: (103010-584)

Supplier: Anaspec Inc

Description: This human recombinant SIRT2 is in its active form, and can be used for enzyme activity assays. The recombinant human Sirtuin 2 (GenBank Accession #: NM_030593) with 13-319 amino acids and His tag at its C-terminal was expressed in E. coli. The molecular mass of the enzyme is approximately 35.5 kDa on SDS-PAGE.
Sirtuins comprise a unique class of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases (class III HDACs) targeting multiple protein substrates.
Sirtuin 1 (SIRT1), the human homolog of yeast Sir2 (Silent Information Regulator 2), is the most studied of the seven members of sirtuin family. SIRT1 have been implicated in several important cellular processes, including genomic stability and DNA repair, p53-mediated apoptosis, adipogenesis, and aging.
Substrates for SIRT2 are not limited to histones but also include various transcription factors and co-regulators that modulate metabolic, cell cycle and cell death related pathways. Human SIRT2 is a cytoplasmic protein that increases in abundance during mitosis and regulates major events of cytokinesis.

Catalog Number: (103010-524)

Supplier: Anaspec Inc

Description: Tissue-type plasminogen activator (tPA) is a serine protease that cleaves pro-enzyme plasminogen into active plasmin

Catalog Number: (103010-952)

Supplier: Anaspec Inc

Description: Spectrally similar to Cy7 dye, HiLyte™ Fluor 750 C2 maleimide is the longest-wavelength thiol-reactive HiLyte™ Fluor dye currently available.

Catalog Number: (103010-946)

Supplier: Anaspec Inc

Description: Spectrally similar to Cy7 dye, HiLyte™ Fluor 750 acid, SE is the longest-wavelength amine-reactive HiLyte™ Fluor dye currently available.