You Searched For: DSP (Dithiobis(succinimidyl propionate))

Supplier: TCI America

Description: [Cross-linking Reagent] CAS Number: 57757-57-0 MDL Number: MFCD00042045 Molecular Formula: C14H16N2O8S2 Molecular Weight: 404.41 Purity/Analysis Method: <gt/>97.0% (N) Form: Crystal Melting point (°C): 133 Storage Temperature: 0-10°C

SDS

Catalog Number: (EM322133-100MG)

Supplier: MilliporeSigma

Description: Bifunctional cross-linker. The disulfide bond can be cleaved with 1% NaBH4, 50 mM DTT, or 100 mM β-mercaptoethanol. Has been used to immobilize proteins on supports containing amino groups.

Certificates

Catalog Number: (82022-782)

Supplier: G-Biosciences

Description: Dithiobis(succinimidyl propionate) Homobifunctional Cross Linker.

Supplier: Ambeed

Description: Di(N-succinimidyl) 3,3-Dithiodipropionate [Cross-linking Reagent], Purity: 97%, CAS Number: 57757-57-0, Appearance: White to off-white solid, Storage: Inert atmosphere, 2-8 C, Size: 1g

Catalog Number: (103523-924)

Supplier: Invitrogen

Description: Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.

Certificates

Supplier: Invitrogen

Description: Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.

SDS Certificates