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Supplier: Adipogen
Description: AMG-1 is a potent inhibitor of human c-Met and RON with IC(50) values of 4 and 9nM respectively.

Supplier: Adipogen
Description: Amidoxime fungicide used in agroculture. Active against powdery mildew of various crops in pre and post infection treatment. Has a long lasting translaminar and vapor phase activity. The mode of action is not know and it is considered different from that of other existing fungicides. It has favorable toxicological, ecotoxicological and environmental profiles. Compound can be used as analytical reference material.

Supplier: Adipogen
Description: Building block for synthesis.

Supplier: Adipogen
Description: Key metabolite of the ketolytic pathway generating acetyl-CoA. Stereoselective product of D-3-hydroxybutyrate dehydreogenase. Clinically and physiologically significant stereoisomer. Energy carrier from adipocytes to peripheral tissues during fasting or exercise. Endogenous inhibitor of histone deacetylases (HDACs) 1, 3 and 4. Ligand of free fatty acid receptor 3 (FFAR3; GPR41) and hydroxycarboxylic acid receptor 2 (HCAR2; GPR109B). NLRP3 inflammasome inhibitor. Prevents K+-efflux and reduces ASC oligomerization and speck formation.

Supplier: Adipogen
Description: Fluorogenic substrate.

Catalog Number: (102980-438)
Supplier: Adipogen
Description: Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK)


Supplier: Adipogen
Description: Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.

Supplier: Adipogen
Description: Widely-used fluorescent indicator for estimating intracellular pH. This membrane-permeant compound is modified by intracellular esterases to produce BCECF, a polar fluorescein derivative that is retained by cells. Intracellular BCECF is stable and has an efflux half-life of greater than two hours.

Catalog Number: (102979-330)
Supplier: Adipogen
Description: The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.


Supplier: Adipogen
Description: Coumarin derivative. Fluorescent label. Shown to be UVA-phototoxic against F. cultnorum and to have some weak biological activities.

Supplier: Adipogen
Description: R406 is a strong Syk inhibitor with an IC(50) of 41nM. It inhibits Syk but not Lyn. It shows 5-fold less potency to Flt3.

Supplier: Adipogen
Description: DAF-2 DA is probably the most successful indicator for nitric oxide. As with other fluorescein diacetates, DAF-2 diacetate is membrane permeant and is deacetylated by intracellular esterases to 4,5-diaminofluorescein (DAF-2).

Supplier: Adipogen
Description: N-terminal modification of peptides in automated synthesis.

Supplier: Adipogen
Description: Reticulol is a cyclic adenosine 3',5'-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor.

Small Business Enterprise

Supplier: Adipogen
Description: Nitric oxide (NO) independent, superoxide-sensitive soluble guanylyl cyclase (sGC) activator. Induces concentration-dependent increase in cGMP levels. Inhibits platelet adhesion to collagen. Thombosis inhibitor. Non-specific phosphodiesterase inhibitor. Na+ channel blocker. Anticancer compound. HIF-alpha inhibitor. Blocks angiogenesis. Tumor growth inhibitor. Apoptosis inducer. NK cell differentiation enhancer. TRAIL sensitizer.

Small Business Enterprise

Supplier: Adipogen
Description: Fluorescent dye which is widely used for staining polymer particles, but also organelles or materials used in medicine.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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