You Searched For: Diagnostic Biosystems

Supplier: Diagnostic Biosystems

Description: Clone2B11+Pd7/26 .5Ml

Supplier: Diagnostic Biosystems

Description: This antibody is specific to a protein of 20 kDa known as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. This antibody does not cross-react with MAGE-1or tyrosinase. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. This antibody stains melanomas and other tumors showing melanocytic differentiation.

Catalog Number: (95025-224)

Supplier: Diagnostic Biosystems

Description: Biotinylated Goat anti Mouse & anti Rabbit IgG Secondary Antibody.

Catalog Number: (99990-154)

Supplier: Diagnostic Biosystems

Description: RTU HRP label for IHC.

Catalog Number: (99990-990)

Supplier: Diagnostic Biosystems

Description: Clone number 56C6, This antibody is specific to human CD10 antigen of 100 kD, also known as common acute lymphocytic leukemia antigen (CALLA). CD10 antigen has been identified on the surface of early lymphoid progenitor cells, immature B cells with in adult bone marrow and germinal center B cells with in lymphoid tissue.

Supplier: Diagnostic Biosystems

Description: CD138, also known as Syndecan-1, is a member of the transmembrane heparan sulfate proteoglycan family, acts as an extracellular matrix receptor and is involved in many cellular functions, including cell-cell adhesion and cell-matrix adhesion. CD138 expression is found in both hematopoietic and non-hematopoietic cells. In the hematopoietic system, CD138 labels plasma cells. It is an excellent marker for plasmacytic differentiation within the spectrum of hematologic malignancy. Among non-hematolymphoid cells, CD138 reactivity is observed in many types of epithelial cells and stoma cells in both normal and tumor tissues.

Catalog Number: (10065-090)

Supplier: Diagnostic Biosystems

Description: The combined detection of p504S, p40 and high molecular weight cytokeratin markers has been shown to be useful for distinguishing benign conditions mimicking cancer from prostate carcinomas. In particular, these markers have been shown to be relevant in diagnosing the premalignant condition, prostatic intraepithelial neoplasia (PIN). High molecular weight cytokeratin and p63 are commonly used markers of basal epithelial cells. Benign prostate tissue contains basal cells, which are absent in prostate cancers. As p40 is an isoform of p63, it also stains basal epithelial cells and can be used in prostate cancer tissue. P504S has been recently described as a prostate cancer-specific gene. Expression of p504S (AMACR) protein is seen in prostatic adenocarcinoma but not in benign prostatic tissue. Anti-p540S stains premalignant lesions of prostate: high-grade PIN and atypical adenomatous hyperplasia. The PIN5 antibody combination may be particularly useful for confirming the diagnosis of prostate carcinoma in small foci of needle biopsies. The positive prostate cancer marker, p504S (AMACR), in conjunction with the negative basal cell markers (p40 and HMW cytokeratin) offers utility in diagnosing PIN in difficult cases where tissue may be limited.

Catalog Number: (95027-172)

Supplier: Diagnostic Biosystems

Description: This kit stains strongly sulfated mucosubstances

Catalog Number: (10098-720)

Supplier: Diagnostic Biosystems

Description: PermaRed/AP-Auto produces a red color, ranging from pink to brilliant dark red, depending on the signal intensity

Supplier: Diagnostic Biosystems

Description: The Mouse/Rabbit PolyVue HRP/DAB Detection System is a polymer-based 1-step horseradish peroxidase-labeled detection system for immunohistochemistry.

Supplier: Diagnostic Biosystems

Description: UnoVue Rabbit AP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections.

Supplier: Diagnostic Biosystems

Description: UnoVue Mouse AP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections.

Supplier: Diagnostic Biosystems

Description: UnoVue Mouse/Rabbit HRP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections.

Catalog Number: (10064-762)

Supplier: Diagnostic Biosystems

Description: Tissue Primer is a universal enzyme blocking reagent to use in horse radish peroxidase (HRP) and alkaline phosphatase (AP) based immunohistochemical staining procedures done on paraffin tissue sections, frozen tissue sections and cell smears to suppress nonspecific staining due to endogenous enzyme activity.

Supplier: Diagnostic Biosystems

Description: Mono AEC/Plus is a liquid substrate chromogen system for use with horseradish peroxidase (HRP) detection in immunohistochemistry (IHC) or <i>in situ</i> hybridizations (ISH).

Supplier: Diagnostic Biosystems

Description: ERG, the ETS related gene, belongs to the ETS family that plays important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The ERG antibody identifies endothelial cells, lymphocytes and prostate cancer cells.