GSK1120212 ~99.5%
Supplier: SELLECK CHEMICALS LLC MS
Synonyms:
N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide, Trametinib, JTP-74057
S2673-5MG
S2673-10MG
S2673-50MG
101759-296EA
192.31
USD
101759-296
101759-298
101759-300
GSK1120212 ~99.5%
GSK1120212
Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.
Formula:
C₂₆H₂₃FIN₅O₄ MW: 615.4 g/mol |
MDL Number:
MFCD17215075 CAS Number: 871700-17-3 |
Specification Test Results
DMSO | 22 mg/mL warmed (35.74 mM) |
Water | Insoluble |
E/E | Insoluble |
4% DMSO+corn oil | 3 mg/mL |
Purity (HPLC) | 99.65% |
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