Human Recombinant DLL4 (from HEK293 Cells)
Supplier: ADIPOGEN CORP MS
AG-40A-0077Y-C010
AG-40A-0077Y-C050
102980-054EA
332.31
USD
102980-054
102980-056
Human Recombinant DLL4 (from HEK293 Cells)
Proteins and Peptides
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
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