OCH ≥95%

Supplier: ADIPOGEN CORP MS

Synonyms: (2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-tetracosanoyl-2-amino-1,3,4-nonanetriol)

AG-CR1-3593-C250 AG-CR1-3593-M001

102988-696EA 180 USD

102988-696 102988-698

OCH ≥95%

OCH

Truncated analog of alpha-GalCer. iNKT cell glycolipid agonist. Immunosuppressive. Th2 polarizing. Stimulation of NKT with OCH results in release of primarily Th2 cytokine compared to stimulation with alpha-GalCer, which results in release of a mixture of Th1 and Th2 cytokines. Induces stronger interleukin-4 (IL-4) secretion and weaker interferon-gamma (IFN-gamma) secretion than alpha-GalCer both in vitro and in vivo. Inducer of interleukin-10 (IL-10) and suppressor of diabetes. Shown to prevent experimental autoimmune encephalomyelitis (EAE) in mice, an animal model of multiple sclerosis. Has beneficial effects on type I diabetes in NOD mice. Suppressor of collagen-induced arthritis. Might be useful for immunotherapy of transplant rejection.

Formula: C₃₉H₇₇NO₉
MW: 704 g/mol
Storage Temperature: Freezer

CAS Number: 383187-82-4

Specification Test Results

Purity	95%
Appearance/Color	White to off-white solid.
Solubility	Soluble in DMSO, 100% ethanol (warm) or methanol (warm).

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