Heptelidic Acid ≥95%
Supplier: ADIPOGEN CORP MS
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Warning
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Synonyms:
Koningic acid, BRN 5091359, Avocettin, FO-4443
Antibiotic
Source/Host: Isolated from Trichoderma sp.
Purity: >95% (HPLC)
Appearance/Color: White solid.
Solubility: Soluble in DMSO, ethanol, methanol or water.
Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.
Formula:
C₁₅H₂₀O₅ Storage Temperature: Freezer |
CAS Number:
74310-84-2 |
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