Heptelidic Acid ≥95%

Supplier: ADIPOGEN CORP MS
Warning

Synonyms: Koningic acid, BRN 5091359, Avocettin, FO-4443

AG-CN2-0118-C250 AG-CN2-0118-M001
102987-966EA 166.15 USD
102987-966 102987-968
Heptelidic Acid ≥95%
Heptelidic Acid

Antibiotic


Source/Host: Isolated from Trichoderma sp.
Purity: >95% (HPLC)
Appearance/Color: White solid.
Solubility: Soluble in DMSO, ethanol, methanol or water.


Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.

Formula: C₁₅H₂₀O₅
Storage Temperature: Freezer
CAS Number: 74310-84-2

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