Calphostin C

Supplier: ADIPOGEN CORP MS

AG-CN2-0430-C100 AG-CN2-0430-M001
102988-254EA 290.77 USD
102988-254 102988-256
Calphostin C
Calphostin C

Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion

Formula: C₄₄H₃₈O₁₄
MDL Number: MFCD00133155
CAS Number: 121263-19-2

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