MLN-9708

Supplier: SELLECK CHEMICALS LLC MS

Synonyms: Ixazomib, MLN9708, 4-(Carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid

S2181-5MG S2181-50MG
101760-680EA 223.08 USD
101760-680 101760-682 101760-684
MLN-9708
MLN-9708

MLN9708 gets hydrolyzed to its biologically active form MLN2238, on exposure to aqueous solutions or plasma


MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2.

Formula: C₂₀H₂₃BCl₂N₂O₉
MW: 517.12 g/mol
MDL Number: MFCD18251437
CAS Number: 1201902-80-8

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