MLN-9708
Supplier: SELLECK CHEMICALS LLC MS
Synonyms:
Ixazomib, MLN9708, 4-(Carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid
S2181-5MG
S2181-50MG
101760-680EA
223.08
USD
101760-680
101760-682
101760-684
MLN-9708
MLN-9708
MLN9708 gets hydrolyzed to its biologically active form MLN2238, on exposure to aqueous solutions or plasma
MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2.
Formula:
C₂₀H₂₃BCl₂N₂O₉ MW: 517.12 g/mol |
MDL Number:
MFCD18251437 CAS Number: 1201902-80-8 |
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