6-ECDCA ≥95%
Supplier: ADIPOGEN CORP MS
Synonyms:
Obeticholic acid, (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid, INT-747
Potent and selective FXR agonist (EC50= 99nM). Induces SHP in HSCs to suppress TIMP-1 expression. Apoptosis inducer. Protects against liver fibrosis development in rat in vivo. Displays anticholeretic activity in rat in vivo. Promotes preadipocyte differentiation. Regulates adipogenesis and insulin signaling in vivo. Inhibits vascular smooth muscle cell inflammation and migration.
Formula:
C₂₆H₄₄O₄ Storage Temperature: Freezer |
MDL Number:
MFCD16621104 CAS Number: 459789-99-2 |
Specification Test Results
Purity |
|
Appearance/Color | White solid. |
Solubility | Soluble in ethanol, methanol, or DMSO. Slightly soluble in water, dichloromethane and acetone. |
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