Human Recombinant TRAILR1 (from HEK293 Cells)

Supplier: ADIPOGEN CORP MS

AG-40B-0070-C050 AG-40B-0070-3050
102515-530EA 249.23 USD
102515-530 102515-532
Human Recombinant TRAILR1 (from HEK293 Cells)
Proteins and Peptides

TRAIL-R1 (DR4; CD261) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

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