DMS (Dimethyl suberimidate dihydrochloride), Pierce™

Supplier: LIFE TECHNOLOGIES MS
Warning

20700
PI20700EA 230.15 USD
PI20700
DMS (Dimethyl suberimidate dihydrochloride), Pierce™
DMS (Dimethyl suberimidate dihydrochloride)

Thermo Scientific Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.


  • Reactive groups: imidoester (both ends)
  • Reactive towards: amino groups (primary amines)
  • Longest of three similar imidoester crosslinkers, which include DMA, DMP and DMS
  • Water-soluble
  • Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
  • Amidine bond retains net charge character of protein primary amine to which it reacts
  • Reversible at high pH values
  • Tool for study of quarternary structure of proteins


Caution: For Research Use Only. Not for use in diagnostic procedures.

Formula: C₁₀H₂₀N₂O₂
Storage Temperature: Refrigerator
MDL Number: MFCD00012574
CAS Number: 34490-86-3

Order Now

Specification Test Results

Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Imidoester
Spacer Mid-Length
Form Powder
Quantity 1 g
Type Crosslinker
Solubility Water
Spacer Arm 11.0 Å


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR