SensoLyte® Rh110 Plasmin Activity Assay Kit (Fluorimetric), AnaSpec Inc.
Supplier: Anaspec Inc
Plasmin belongs to the family of serine proteases
The SensoLyte® Rh110 Plasmin Activity Assay Kit provides a convenient assay for high throughput screening of plasmin inhibitors and inducers or for continuous assay of plasmin activity utilizing a fluorogenic peptide. Upon enzyme cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=496 nm/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from reaction components. Assays are performed in a convenient 96-well microplate format.
It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.
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