[Lys(Ac)9]-Histone H3 (1-24)
Supplier: Anaspec Inc
AS-64453
103008-178EA
339.08
USD
103008-178
[Lys(Ac)9]-Histone H3 (1-24)
Proteins and Peptides
This Histone 3 peptide is acetylated at lysine residue at 9th position. In a glioblastoma xenograft expressing a O6-methylguanine-DNA methyltransferase (MGMT), increased H3K9-ac was observed in correlation to histone acetylation and MGMT upregulation, thus demonstrating a mechanism driven by chromatin-mediated MGMT upregulation in potentially directing epigenetic therapies to influence the mechanisms of resistance development in glioblastomas.
Sequence:ARTKQTAR-K(Ac)-STGGKAPRKQLATKA
MW:2597 Da
% peak area by HPLC:95
Storage condition:-20° C
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