Glutamic Acid Decarboxylase (GAD65) (524-543)

Supplier: Anaspec Inc

AS-62757
103007-512EA 239.69 USD
103007-512
Glutamic Acid Decarboxylase (GAD65) (524-543)
Proteins and Peptides

This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.
Sequence:SRLSKVAPVIKARMMEYGTT
MW:2238.7 Da
% peak area by HPLC:95
Storage condition:-20° C

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