Glutamic Acid Decarboxylase (GAD65) (524-543)
Supplier: Anaspec Inc
This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.
Sequence:SRLSKVAPVIKARMMEYGTT
MW:2238.7 Da
% peak area by HPLC:95
Storage condition:-20° C
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