Trp Cage
Supplier: Anaspec Inc
This C-terminal Exendin 4 Trp Cage variant is known as TC5b and can be used an for simulation studies of protein folding. This 20-residue construct is over 95% folded in water at physiological pH, and exhibits a tightly folded tertiary structure in solution. Trp Cage is a highly stable mini-protein fold. It consists of a short helix, a 3,10 helix and a C-terminal poly-proline that packs against a Trp in the alpha helix. It is known to fold within 4 nanoseconds. This stable fast-folding Trp Cage sequence displays special stabilizing features specific to this miniprotein.
Sequence: NLYIQWLKDGGPSSGRPPPS
MW: 2169.4 Da
% Peak area by HPLC: 95
Storage condition: -20° C
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