6-(Dimethylamino)purine
Supplier: ADIPOGEN CORP MS
A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-alpha upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).
Formula:
C₇H₉N₅ |
MDL Number:
MFCD00005573 CAS Number: 938-55-6 |
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