Fostriecin sodium salt ≥98%

Supplier: ADIPOGEN CORP MS

Irritant Warning

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Synonyms: (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt, Fostriecin

AG-CN2-0057-C010

102987-176EA 228.46 USD

102987-176

Fostriecin sodium salt ≥98%

Fostriecin sodium salt

Antibiotic

Source/Host: Isolated from Streptomyces pulveraceous subsp. fostreus.
Purity: >98% (HPLC)
Appearance/Color: Colorless solid.
Solubility: Soluble in water, methanol or ethanol.

Anticancer compound. Antifungal. Catalytic inhibitor of topoisomerase II (IC50 = 40 µM). Potent protein phosphatase 2A (PP2A) (IC50 = 1.5 nM) and 4 (PP4) (IC50 = 3 nM) inhibitor. Weak protein phosphatase type 1 (PP1) inhibitor (IC50=131µM). No apparent inhibition on PP2B. Mitotic entry checkpoint inhibitor. Mediates cell cycle arrest at G2-M-phase. Ischemia protective. The PP2A binding site is different from that of okadaic acid

Formula: C₁₉H₂₆O₉PNa
Storage Temperature: Freezer

CAS Number: 87860-39-7

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