Mouse Recombinant DLL4 (from HEK293 Cells)

Supplier: ADIPOGEN CORP MS

AG-40A-0145-C010 AG-40A-0145-C050
102515-212EA 152.31 USD
102515-212 102515-214
Mouse Recombinant DLL4 (from HEK293 Cells)
Proteins and Peptides

The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

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