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Anti-CD75 Monoclonal Antibody [clone: LN1]

Catalog Number: (102512-592)
Supplier: Adipogen
Description: Human CD75 is an alpha 2, 6-sialylated carbohydrate molecule found mainly on mature B cells and germinal center B cells and also in T cell subsets and erythrocitic cells. CD75 appears to be a ligand for CD22.

Small Business Enterprise


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Anti-CD95 Monoclonal Antibody (Biotin) [clone: ANC95.1]

Catalog Number: (102512-932)
Supplier: Adipogen
Description: Human CD95 (APO-1; Fas) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for regulating the immune response.

Small Business Enterprise


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Anti-CD86 Monoclonal Antibody (FITC) [clone: BU63]

Catalog Number: (102512-902)
Supplier: Adipogen
Description: Human CD86 (B7-2) is a costimulating ligand for CD28 and CTLA-4. CD86 is expressed on activated B cells and blood monocytes.

Small Business Enterprise


Image Unavailable-102512-880

Anti-CD83 Monoclonal Antibody (Biotin) [clone: HB15e]

Catalog Number: (102512-880)
Supplier: Adipogen
Description: Human CD83 is a type 1 cell surface glycoprotein expressed almost solely by dendritic cells that play an important role in antigen presentation.

Small Business Enterprise


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Anti-CD81 Monoclonal Antibody [clone: 1.3.3.22]

Catalog Number: (102512-868)
Supplier: Adipogen
Description: Human CD81 is a member of the tetraspan family of leukocyte cell surface molecules which are involved in signal transduction, cell-cell adhesion and cellular activation. Association of CD81 with integrins appears to be functionally important in the regulation of cell adhesion and activation. Recent work with CD81-null mice indicates CD81 is important for development of humoral immune response.

Small Business Enterprise


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Anti-CD79B Monoclonal Antibody [clone: SN8]

Catalog Number: (102512-856)
Supplier: Adipogen
Description: Human CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta) which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg) (3). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer transduces signals. Analysis of CD79b expression is useful in diagnosis of B cell lymphoproliferative disorders.

Small Business Enterprise


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Anti-CD79B Monoclonal Antibody (R-PE) [clone: SN8]

Catalog Number: (102512-864)
Supplier: Adipogen
Description: Human CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta) which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg) (3). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer transduces signals. Analysis of CD79b expression is useful in diagnosis of B cell lymphoproliferative disorders.

Small Business Enterprise


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Human Recombinant Progranulin (from HEK293 Cells)

Supplier: Adipogen
Description: Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

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XL765 ≥95%

Supplier: Adipogen
Description: XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM)

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AMG-1 ≥95%

Supplier: Adipogen
Description: AMG-1 is a potent inhibitor of human c-Met and RON with IC(50) values of 4 and 9nM respectively.

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CH5132799 ≥95%

Supplier: Adipogen
Description: CH5132799 selectively inhibits class I PI3Kalpha with an IC(50) value of 14nM.

Image Unavailable-102989-688

N-Succinimidyl 4-[4-(Dimethylamino)phenylazo]benzoate

Supplier: Adipogen
Description: N-terminal modification of peptides in automated synthesis.

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p-Xylenol Blue

Supplier: Adipogen
Description: Sulfonephthalein dye. Acid-base pH indicator dye with pH ranges of pH 1.2 (Red) - pH 2.8 (Yellow), and pH 8.0 (Yellow) - pH 9.6 (Blue). Spectral data: Absorption, lambdamax 424nm. Has been used as pH sensor, indicator, in cosmetics and drug applications, microbiological assays and determining lipases.

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Zinquin free acid ≥95% (by HPLC)

Supplier: Adipogen
Description: Used to detect zinc in cells by UV fluorescence.

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Bayer-18 ≥95%

Supplier: Adipogen
Description: Bayer-18 is a selective TYK2 inhibitor, with an IC(50) of 18.7nM on TYK2 as measured by TYK2 HTRF assays. The compound shows 1000 fold selectivity against JAK2, CDK and KDR kinases in similar HTRF assays.

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Altersolanol A ≥97% (by HPLC)

Catalog Number: (102988-268)
Supplier: Adipogen
Description: Anticancer compound. Apoptosis inducer. Anti-angiogenic. Anti-inflammatory. Antibacterial. Phytotoxic.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
To process your orders without delay, please provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:

  • State issued document with your organization's Federal Tax ID Number
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  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name & address

* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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