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Supplier: MilliporeSigma
Supplier: MilliporeSigma

SDS

Catalog Number: (EM1.13861.0025)
Supplier: MilliporeSigma
Description: Cas Number: 3006-15-3, Synonyms: 2-Sulfosuccinic Acid Di-N-Hexyl Ester Sodium Salt, 25G

Catalog Number: (100219-890)
Supplier: Teknova
Description: Ampicillin is used as a selectable marker in many commonly used plasmids. A functional Ampicillin gene will confer resistance to cells containing the plasmid.


Catalog Number: (100216-960)
Supplier: Teknova
Description: Chloramphenicol is a broad-spectrum antibiotic effective against most strains of Gram-positive and Gram-negative bacteria.


Supplier: Honeywell Research Chemicals
Description: ACS GENERAL USE SOLVENTS

SDS

Supplier: MP Biomedicals
Description: Cefoperazone sodium salt is used to study drug-protein binding, expression and inhibition of penicillin-binding proteins (PBPs) during cell wall synthesis.
Supplier: MP Biomedicals
Description: Folic Acid antagonist; structurally similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds.

SDS

Supplier: MP Biomedicals
Description: D-Pantothenic acid is an essential vitamin (except in horses, ruminants). Pantothenic acid is involved in a number of biological reactions including: A precursor in the biosynthesis of coenzyme A, production of energy, catabolism of fatty acids and amino acids, synthesis of fatty acids, phospholipids, sphingolipids, cholesterol and steroid hormones, synthesis of heme and the neurotransmitter acetylcholine and involved in regulation of gene expression and in signal transduction.

SDS

Supplier: MP Biomedicals
Description: Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.

Supplier: MP Biomedicals
Description: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis.

Supplier: Adipogen
Description: Aminoglycoside antibiotic. Protein synthesis inhibitor. Causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. Antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas. Used as a selection agent (gentamicin-resistance gene) in molecular biology applications. Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies. Bactericidal effects are exerted by the binding to the outer membrane, causing disruption of the membrane. This increases the permeability of the cell envelope, leakage of cell contents, and leading to apoptosis and proteolysis (cell death). Causes also cell death by generation of free radicals, phospholipidosis, extracellular calcium-sensing receptor stimulation and energetic catastrophe.

Supplier: MP Biomedicals
Description: Gentamicin sulfate is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M

SDS

Supplier: MP Biomedicals
Description: Calcium chloride is useful in preparing competent bacteria. Calcium chloride dihydrate was used in the preparation of calcium-alginate beads. It was used to compose the medium for Thermophilic Clostridia (MTC). It may be used for the concentration of virus vectors in a protocol. Store at Room Temperature (15-30 °C). Store Desiccated. Physical Appearance: White Powder Solubility: Soluble in water with heat liberation, ethanol, acetic acid, acetone. pH: 4.5-9.2 (5% aq soln) Heavy Metals: ≤0.001%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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