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Catalog Number: (10670-518)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin.


Catalog Number: (77524-254)
Supplier: AFG Bioscience
Description: Human UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1) ELISA Kit


Catalog Number: (77526-660)
Supplier: AFG Bioscience
Description: Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA kit


Catalog Number: (10100-328)
Supplier: Prosci
Description: LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Catalog Number: (76710-272)
Supplier: AFG Bioscience
Description: Mouse Long-chain-fatty-acid--CoA Ligase 1(ACSL1) ELISA Kit


Catalog Number: (10671-954)
Supplier: Bioss
Description: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.


Catalog Number: (10494-102)
Supplier: Bioss
Description: Exhibits weak E3 ubiquitin-protein ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Can ubiquitinate AKT1 preferentially at 'Lys-284' involving 'Lys-48'-linked polyubiquitination and seems to be involved in regulation of Akt signaling by targeting phosphorylated Akt to proteosomal degradation. Proposed to preferentially act as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. The function may implicate its abilty to sumoylate DNM1L. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. Involved in the modulation of innate immune defense against viruses by inhibiting DDX58-dependent antiviral response. Can mediate DDX58 sumoylation and disrupt its polyubiquitination.


Catalog Number: (77512-924)
Supplier: AFG Bioscience
Description: Human GCLM (Glutamate Cysteine Ligase, Modifier Subunit) ELISA Kit


Catalog Number: (ABCA_AB155511-100U)
Supplier: Abcam
Description: Rabbit polyclonal to E3 ubiquitin-protein ligase MUL1.

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Catalog Number: (76715-146)
Supplier: AFG Bioscience
Description: Human E3 Ubiquitin Protein ligase CHIP (STUB1) ELISA Kit


Catalog Number: (76699-294)
Supplier: AFG Bioscience
Description: Human E3 Ubiquitin Protein Ligase MIB2 (MIB2) ELISA Kit


Catalog Number: (76712-304)
Supplier: AFG Bioscience
Description: Human E3 Ubiquitin-Protein Ligase CBL (CBL) ELISA Kit


Catalog Number: (76110-356)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin.


Supplier: Abcam
Description: Rabbit monoclonal [EPR20241] to E3 ubiquitin-protein ligase MUL1 - BSA and Azide free.

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Catalog Number: (10102-700)
Supplier: Prosci
Description: Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.


Catalog Number: (89357-872)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to GCLM (glutamate-cysteine ligase, modifier subunit)


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