You Searched For: DNases

Catalog Number: (10466-612)

Supplier: Bioss

Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: ULTRAPURE BIOREAGENT—A line of high purity reagents tested for use in biotechnology applications, such as electrophoresis, and liquid chromatography. Where applicable, tests include DNase, RNase, Protease, heavy metals and insoluble matter.

Certificates

Catalog Number: (102210-090)

Supplier: Novus Biologicals

Description: The DNase II Antibody from Novus Biologicals is a rabbit polyclonal antibody to DNase II. This antibody reacts with human. The DNase II Antibody has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Catalog Number: (PAM6101)

Supplier: Promega Corporation

Description: RQ1 (RNA Qualified) RNase-Free DNase is a DNase I that degrades both double-stranded and signle-stranded DNA.

Certificates

Supplier: VWR

Description: Tested to be nuclease, Dnase and/or protease free where applicable. Appropriate for use in Proteomic research applications.

SDS Certificates

Catalog Number: (10801-162)

Supplier: Rockland Immunochemical

Description: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kDa proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.

Supplier: MilliporeSigma

Description: Native DNase I from bovine pancreas.

SDS Certificates

Catalog Number: (ABCA_AB113241-50UL)

Supplier: Abcam

Description: Rabbit polyclonal to DNase I.

New Product

Catalog Number: (10466-610)

Supplier: Bioss

Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.

Catalog Number: (10466-604)

Supplier: Bioss

Description: Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.

Catalog Number: (IC821739)

Supplier: MP Biomedicals

Description: Sterile water. Deionized, treated with 0.001% DEPC, 0.2µm filtered, and autoclaved. DNase- and RNase-free.

SDS

Supplier: Agilent Technologies

Description: Purified DNase I tested to be free of contaminating activity for the degradation of nucleic acids.

Catalog Number: (75856-400)

Supplier: MP Biomedicals

Description: DNase-free water (DES).

SDS

Catalog Number: (95022-206)

Supplier: HiMedia

Description: For the detection of deoxyribonuclease activity of bacteria and fungi.

SDS

Supplier: STEMCELL Technologies

Description: Animal component-free DNase I for digestion of DNA.

New Product

Supplier: VWR International

Description: VWR® 96-Well PCR Plates are compatible with most leading PCR and real-time PCR instruments.

Certificates