Anti-Galectin-3 Mouse Monoclonal Antibody [clone: H-5]

Supplier: Diagnostic Biosystems

MOB541-05 MOB541

76634-026EA 476.32 USD

76634-026 76634-028 76634-024

Anti-Galectin-3 Mouse Monoclonal Antibody [clone: H-5]

Antibodies

Galectin-3 is a member of the beta-galactoside-binding protein family that plays an important role in cell adhesion, cell matrix interactions, macrophage activation, angiogenesis, metastasis, and apoptosis.

Galectin-3 shows strong diffuse cytoplasmic staining in most cases of papillary thyroid carcinoma (PTC), most poorly differentiated thyroid cancers demonstrate galectin-3 protein expression while it is not expressed in anaplastic thyroid cancers. (1) Upregulated expression of galectin-3 is involved in cancer progression and metastasis, and it is suggested that Galectin-3 may be a valuable tool to support diagnosis of parathyroid carcinoma. (2)

Galectin-3 has also been reported to play important roles in the progression of prostate cancer, and their heterogeneous expressions might be associated with different cancer subtypes. (3)

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