Anti-Histiocytoma Marker Mouse Monoclonal Antibody (CF594) [clone: D11]

Supplier: Biotium

BNC940348-100 BNC940348-500
75950-530EA 205.77 USD
75950-530 75950-532
Anti-Histiocytoma Marker Mouse Monoclonal Antibody (CF594) [clone: D11]
Antibodies
In Western blotting, this antibody detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: Histiocytoma Marker
Clonality: Monoclonal
Clone: Clone D11
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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