Mouse Recombinant Notch1 (from CHO Cells)

Supplier: 0000027161

AG-40B-0109-C050 AG-40B-0109-3050
102980-162EA 332.31 USD
102980-162 102980-164
Mouse Recombinant Notch1 (from CHO Cells)
Proteins and Peptides

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

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