Mouse Recombinant IL-13 (from E. coli)

Supplier: Peprotech

210-13-2UG 210-13-10UG 210-13-50UG 210-13-100UG 210-13-250UG 210-13-500UG 210-13-1MG

10779-962EA 141.24 USD

10779-962 10779-964 10779-966 10779-968 10779-970 10779-972 10779-974

Mouse Recombinant IL-13 (from E. coli)

Proteins and Peptides

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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