Human Recombinant sTRAIL (from E. coli)

Supplier: Peprotech

310-18-10UG 310-18-50UG 310-18-100UG 310-18-250UG 310-18-500UG 310-18-1MG
10774-282EA 132.81 USD
10774-282 10774-284 10774-286 10774-288 10774-290 10774-292
Human Recombinant sTRAIL (from E. coli)
Proteins and Peptides

TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins, and contain a cytoplasmic "death domain," which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane-anchored or soluble TRAIL/Apo2L. The DR4 and DR5 receptors are both produced as type I transmembrane proteins, which contain an extracellular domain, a transmembrane domain, and a cytoplasmic domain. The recombinant soluble forms of DR4 and DR5 consist of the TNFR-homologous, cysteine-rich portion of their respective extracellular domains. Recombinant Human sTRAIL Receptor-1 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine-rich portion of the extracellular domain.


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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