Anti-CASP4 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals
600-401-AD0
10800-554EA 518 USD
10800-554
Anti-CASP4 Rabbit Polyclonal Antibody
Antibodies
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.

Recommended Dilutions: ELISA: 1:10,000; Immunohistochemsitry: 10 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CASP4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat
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