Anti-DNASE2 Rabbit Polyclonal Antibody

Supplier: Proteintech
15934-1-AP-150UL
10086-034EA 453 USD
10086-034
Anti-DNASE2 Rabbit Polyclonal Antibody
Antibodies
DNASE2, or 'acid DNase,' hydrolyzes DNA under acidic conditions and is one of 2 distinct mammalian DNases. It hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. It has a key role in the degradation of nuclear DNA in cellular apoptosis during development . Besieds, it is necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. It has been demonstrated to be responsible forDNA degradation in apoptotic cells engulfed by macrophages and exogenous DNA on the skin surface .

Western Blot: HeLa Cells, 1:200-1:1000

Type: Primary
Antigen: DNASE2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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