Anti-CD44 Rat Monoclonal Antibody (violetFluor® 450) [clone: IM7]

Supplier: Tonbo Biosciences

C57Bl/6 splenocytes were stained with 0.25 ug violetFluor™ 450 Anti-Hu/Mo CD44 (75-0441) (solid line) or 0.25 ug violetFluor™ 450 Rat IgG2b isotype control (dashed line).

C57Bl/6 splenocytes were stained with 0.25 ug violetFluor™ 450 Anti-Hu/Mo CD44 (75-0441) (solid line) or 0.25 ug violetFluor™ 450 Rat IgG2b isotype control (dashed line).

75-0441-U025 75-0441-U100

10051-808EA 94.6 USD

10051-808 10051-810

Anti-CD44 Rat Monoclonal Antibody (violetFluor® 450) [clone: IM7]

Antibodies

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.

The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: violetFluor® 450
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity:

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