Anti-CD19 Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 1D3]

Supplier: Tonbo Biosciences

C57Bl/6 splenocytes were stained with 0.25 ug PE-Cy7 Anti-Mouse CD19 (60-0193) (solid line) or 0.25 ug PE-Cy7 Rat IgG2a isotype control (dashed line).

C57Bl/6 splenocytes were stained with 0.25 ug PE-Cy7 Anti-Mouse CD19 (60-0193) (solid line) or 0.25 ug PE-Cy7 Rat IgG2a isotype control (dashed line).

60-0193-U025 60-0193-U100

10051-468EA 51.7 USD

10051-468 10051-470

Anti-CD19 Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 1D3]

Antibodies

The 1D3 antibody reacts with mouse CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 and CD81, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.

The 1D3 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

Type: Primary
Antigen: CD19
Clonality: Monoclonal
Clone: 1D3
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Rat
Isotype:
Reactivity: Mouse

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