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Anti-C4D Mouse Monoclonal Antibody [clone: C4D204]

Supplier: Diagnostic Biosystems

MOB471 MOB471-05 PDM184

10064-966EA 715.6 USD

10064-966 10064-968 10065-010

Anti-C4D Mouse Monoclonal Antibody [clone: C4D204]

Antibodies

Complement 4d (C4d) is the most clinically used marker for humoral rejection. It is a degradation product of the activated complement factor C4b. Complement 4d is typically initiated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. Complement 4d is also found in intracytoplasmic vacuoles of endothelial cells. Covalent binding renders C4d a stable molecule that can easily be detected by immunohistochemistry.

Type:
Antigen: C4D
Clonality: Monoclonal
Clone: C4D204
Conjugation:
Epitope:
Host: Mouse
Isotype:
Reactivity:

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