T4 RNA Ligase 2, New England Biolabs
Supplier: New England Biolabs (NEB)
M0239L
M0239S
101386-086EA
376
USD
101386-086
101386-088
T4 RNA Ligase 2, New England Biolabs
Nucleic Acid Reagents
Cloning Kits and Ligation
T4 RNA Ligase 2, also known as T4 Rnl2 (gp24.1), has both intermolecular and intramolecular RNA strand joining activity
Unlike T4 RNA Ligase 1, T4 RNA Ligase 2 is much more active joining nicks on double stranded RNA than on joining the ends of single stranded RNA. The enzyme requires an adjacent 5´ phosphate and 3´ OH for ligation. The enzyme can also ligate the 3´ OH of RNA to the 5´ phosphate of DNA in a double stranded structure.
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