EZClick™ Global Protein Synthesis Assay Kit (FACS/Microscopy), Red Fluorescence, BioVision, Inc.

EZClick™ Global Protein Synthesis Assay Kit

EZClick™ Global Protein Synthesis Assay Kit

EZClick™ Global Protein Synthesis Assay Kit

EZClick™ Global Protein Synthesis Assay Kit

EZClick™ Global Protein Synthesis Assay Kit

EZClick™ Global Protein Synthesis Assay Kit

76200-046EA 880.68 USD

76200-046

EZClick™ Global Protein Synthesis Assay Kit (FACS/Microscopy), Red Fluorescence, BioVision, Inc.

Assays Protein Assays

Assay to screen/study/characterize thioredoxin 1 inhibitors.

Rapid, simple and sensitive
Convenient and HTS
Includes inhibitor control

The human Thioredoxin 1 (Trx1) is a key enzyme that protects cells from oxidative stress by reducing disulfides and methionine sulfoxide groups in oxidized proteins. It also regulates DNA repair and apoptosis. In mammals, Trx1 is necessary for growth and development. However, an aberrant elevated expression of Trx1 is known to promote lung, cervical, pancreatic, colorectal, and breast cancers.

The screening kit, Trx1 reduces quenched di-FITC-labeled oxidized glutathione (Trx1 substrate), to mono-FITC-labeled unquenched reduced glutathione. In the presence of a Trx1 inhibitor (control inhibitor included), the reaction is impeded resulting in lower or no signal. The assay is high-throughput adaptable and can be completed in less than 1 hr.

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