Human Recombinant VEGFA

Supplier: Rockland Immunochemical

009-001-B99-0.1
RL009001B990.1EA 867.16 USD
RL009001B990.1
Human Recombinant VEGFA
Proteins and Peptides

VEGF-165 Human Recombinant control protein


  • Control Protein
  • PCA Assays
  • ImmunoBlot


Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as Tumor Angiogenesis Factor or Vascular Permeability Factor. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating vasolidation via nitric oxide-dependent pathways. Alternative splicing of the mRNA for VEGF-A results in several isoforms of the protein being produced. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95 percent.

In contrast to other factors mitogenic for endothelial cells such as FGF-1, FGF-2 and PDGF, VEGF is synthesized as a precursor containing a typical hydrophobic secretory signal sequence of 26 amino acids. Glycosylation is not required for efficient secretion of VEGF. Recombinant Human VEGF produced in E.coli is a double, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 38231 Daltons.


VEGF-165 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-VEGF-165 in immunological assays.

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