Toluene-α-sulfonyl fluoride

Supplier: 0000013509

36978
PI36978EA 135.38 USD
PI36978
Toluene-α-sulfonyl fluoride
Toluene-α-sulphonyl fluoride

Thermo Scientific PMSF is a protease inhibitor that reacts with serine residues to inhibit trypsin, chymotrypsin, thrombin and papain.


  • Targets serine proteases, including trypsin, chymotrypsin, thrombin and papain
  • Effective in most protein solutions at 0.1 to 1 mM final concentration
  • Because PMSF has limited water solubility, it must be dissolved in a small amount of solvent, such as ethanol, methanol or isopropyl alcohol before addition to a buffer


PMSF is an abbreviation for phenylmethylsulfonyl fluoride, the most common chemical name for this small compound


Properties of PMSF:
Synonyms: alpha-Toluenesulfonyl fluoride; Benzylsulfonyl fluoride; Phenylmethylsulfonyl fluoride
Formula: C6H5CH2SO2F
Molecular weight: 174.19
CAS Number: 329-98-6; EC Number: 206-350-2
R/S Codes: R 25-34; S 26-36/37/39-45
Storage conditions: room temperature in a dry place protected from light
Working solution: dissolve PMSF in isopropanol at 1.74 mg/mL (10 mM); store in aliquots at -20˚C.


Specifications of PMSF (Part No. 36978):
Appearance: white powder
Purity:> 99.0 %
Melting point: 90-95˚C
Humidity: < 0.1 %


In addition to inhibiting serine proteases, PMSF will also inhibit cysteine proteases, like papain (reversible by DTT treatment), and mammalian acetylcholinesterase.


Ordering information: Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, between the following temperatures: 20 to 25?C.


Caution: For Research Use Only. Not for use in diagnostic procedures.

Formula: C₇H₇FO₂S
MDL Number: MFCD00007424
CAS Number: 329-98-6

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