2-Morpholino-8-phenylchromone

Supplier: Promega Corporation

2-Morpholino-8-phenylchromone

2-Morpholino-8-phenylchromone

Synonyms: LY294002, LY 294002, 2-Morpholino-8-phenyl-4H-chromen-4-one, 2-Morpholino-8-phenyl-4-oxo-4H-1-benzopyran

V1201

PAV1201EA 235.53 USD

PAV1201

2-Morpholino-8-phenylchromone

2-Morpholino-8-phenylchromone

LY 294002 is a potent and specific cell-permeable inhibitor of phosphatidylinositol 3-kinases (PI 3-kinases).

Potent Inhibitor of Phosphatidylinositol 3-Kinases
Cell-permeable
Specifically inhibits PI 3-kinases
Supplied as a dried powder

LY 294002 [2-(4-Morpholinyl)-8-phenyl-4 H-1-benzopyran-4-one] is a potent and specific cell-permeable inhibitor of phosphatidylinositol 3-kinases (PI 3-kinases) with IC50 values in the 1-50uM range. LY 294002 competitively inhibits ATP binding to the catalytic subunit of PI 3-kinases and does not inhibit PI 4-kinase, DAG-kinase, PKC, PKA, MAPK, S6 kinase, EGFR or c-src tyrosine kinases and rabbit kidney ATPase.

Formula: C₁₉H₁₇NO₃
MW: 307.35 g/mol

MDL Number: MFCD00270881
CAS Number: 154447-36-6

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